Download A Network-Based Approach to Cell Metabolism: From Structure by Oriol Güell PDF

By Oriol Güell

This thesis makes use of a systems-level method of research the mobile metabolism, unveiling new mechanisms and responses that have been very unlikely to arrive with conventional reductionists techniques.

The effects mentioned right here have a possible software in parts like metabolic engineering and illness therapy. they can even be utilized in settling on the accuracy of the gene essentiality of recent genome-scale reconstructions.

Different tools and strategies, in the contexts of structures Biology and the sector referred to as advanced Networks research were utilized during this paintings to teach diversified gains of the robustness of metabolic networks. the explicit concerns addressed the following variety from natural topological aspec

ts of the networks themselves to the stability of biochemical fluxes.


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